Introduction
Endoscopic retrograde appendicitis therapy (ERAT) offers an appendix-preserving approach, yet visual and specificity challenges persist. In contrast, endoscopic direct appendicitis therapy (EDAT) provides direct visual observation with diagnostic and therapeutic capabilities. This study aimed to assess the efficacy and feasibility of EDAT compared to ERAT in uncomplicated appendicitis.
Aims & Methods
We retrospectively reviewed of patients diagnosed with suspected uncomplicated appendicitis undergoing ERAT or EDAT from Jan 2021 to Mar 2024. The primary outcome was to evaluate the intervention success of two groups. The secondary outcomes included hospitalization, procedure time, stent placement, post-procedure hospitalization period, pain relief, recurrence, and endoscopic direct-view characteristics were compared.
Results
Sixty-nine patients were enrolled, among which 34 patients underwent ERAT and 35 patients underwent EDAT. EDAT showed significantly higher intervention success (100% and 85.3%, respectively, p = 0.018), and shorter hospitalization stay (p = 0.003), and post-procedure hospitalization stay (p < 0.001) compared to ERAT group. With comparable procedure time (p = 0.915) and recurrence (p = 0.164), significant fewer proportions of stent placements (p < 0.001), guidewire assists (p < 0.001), and post-procedure antibiotic administrations (p = 0.036) associated in EDAT group compared to ERAT group.
Conclusion
EDAT has demonstrated to be an effective and feasible approach, offering both diagnostic and therapeutic capabilities for uncomplicated appendicitis compared to ERAT.
References
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