1 University of Gothenburg, Gothenburg, Sweden

2 Sahlgrenska University Hospital, Mölndal, Sweden

3 Karolinska University Hospital, Stockholm, Sweden

4 University of Gothenburg, Gothenburg, Sweden|||University of North Carolina at Chapel Hill, Chapel Hill, United States

1 Barts Health NHS Trust, London, United Kingdom

2 Digestive Disorders Clinical Academic Unit, BARTS & THE LONDON SCHOOL OF MEDICINE, London, United Kingdom

1 CHUM, Montreal, Canada|||Université de Montréal, Montréal, Canada

2 Sacre-Coeur Hospital, Montréal, Canada|||Université de Montréal, Montréal, Canada

3 University of Toronto, Toronto, Canada

4 Takeda Canada Inc, Toronto, Canada

5 Pentavere Research Group, Toronto, Canada

6 University of British Columbia, Vancouver, Canada

1 ULS Coimbra, Coimbra, Portugal

1 Campus Bio-medico University, Rome, Italy

2 Campus Bio-medico University, Rome, Italy|||Campus Bio Medico University, Rome, Italy

3 Fondazione Policlinico Campus Bio-Medico di Roma, Rome, Italy

4 Fondazione Policlinico Campus Bio-Medico of Rome, Rome, Italy

5 Bambino Gesù Children's Hospital, IRCCS, Rome, Italy

6 Bambino Gesu Children's Hospital, IRCCS, Rome, Italy

7 Fondazione Comitans, Rome, Italy

8 Campus Bio Medico University, Rome, Italy|||Fondazione Policlinico Campus Biomedico di Roma, Roma, Italy

9 Fondazione Policlinico Campus Biomedico di Roma, Roma, Italy|||Campus Bio Medico University, Rome, Italy

1 Semmelweis University, Budapest, VIII., Hungary

2 Semmelweis University, Budapest, Hungary

3 Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary, Pécs, Hungary