UEG's educational platform for gastroenterology education bringing recordings, courses, guidelines, and more together in one place.

UEG Week Berlin 2025 Recordings Gut Guide online

Rate for better recommendations!

Your feedback helps us show you more of what you like and less of what you dislike!

More of this!

We will show you more similar content.

Not for me!

We won't suggest this again.

Bookmark!

Save this content for later!

New to myUEG? Create an account! Log In with myUEG account

UEG Poster

Standard Poster

Share via Email Share on Facebook Share on X Share on LinkedIn Share on Bluesky

This content is part of Gutflix. Log in with your myUEG account, or create one free, to watch it.

Not sure what you can access? Learn more about account types.

PREDICTORS OF RECURRENCE AFTER ENDOSCOPIC RETROGRADE APPENDICITIS THERAPY FOR ACUTE APPENDICITIS: A MULTI-CENTER COHORT STUDY WITH LONG-TERM FOLLOW-UP IN CHINA

Jiyu Zhang 1, Miao Shi 1, deliang li 1, Lixia Zhao 1, Qingfen Zheng 1, Bingrong Liu 1, Dan Liu 1

Affiliations

1 The First Affilaited Hospital of Zhengzhou University, Zhengzhou, China

Summary

AI Generated

A multi-center retrospective study of 435 patients found that Endoscopic Retrograde Appendicitis Therapy for acute appendicitis achieved 92.4% clinical success with a 16.1% recurrence rate over 37 months median follow-up.

All ERAT procedures were technically successful, with most recurrences (13%) occurring within the first year of the 37-month median follow-up period.
Independent risk factors for recurrence included recurrent appendicitis (HR=1.916), appendiceal lumen distortion (HR=7.996), absence of stent placement (HR=0.375 protective), and operator inexperience (HR=2.318).
Stent implantation effectively minimized recurrence risk, particularly in complicated cases, and ERAT facilitated appendicolith elimination in appendicolith-associated appendicitis.
The study suggests that skilled operators and effective stent placement are crucial for reducing recurrence in complex cases, with findings intended to guide clinical decision-making regarding this minimally invasive alternative to appendectomy.

Download PDF

Was this helpful?

Thanks for your feedback.

This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

Abstract

Introduction

Acute appendicitis is a widely encountered emergency across the globe, showcasing the resilience of modern medicine, as it is traditionally addressed through the transformative procedure of appendectomy. Endoscopic Retrograde Appendicitis Therapy (ERAT) has emerged as a minimally invasive alternative; however recurrence is a worry.

Aims & Methods

This multi-center retrospective study aimed to evaluate the long-term safety, efficacy, and recurrence-related risk factors of ERAT to guide clinical decision-making. A total of 435 patients who underwent ERAT for acute appendicitis between October 2017 and October 2024 at three Chinese medical centers were included. Appendicitis recurrence was defined as imaging-confirmed symptoms returning within one-month post-ERAT. Univariate and multivariate regression analysis identified independent recurrence risk variables.

Results

All ERAT procedures were technically successful and achieved a clinical success rate of 92.4%. Over a median follow-up period of 37 months, the overall recurrence rate was 16.1%, with the majority of recurrences (13%) observed within the first year. Independent risk factors for recurrence included recurrent appendicitis (HR=1.916), appendiceal lumen distortion (HR=7.996), absence of stent placement (HR=0.375, protective), and operator inexperience (HR=2.318). Stent implantation effectively minimizes recurrence risk, especially in complicated incidents. ERAT facilitated overseeing appendicolith elimination, which assisted in occurring appendicolith-associated appendicitis.

Conclusion

ERAT is deemed safe and effective for acute appendicitis, with the highest recurrence risk occurring within the first year. Effective stent placement and skilled operators are crucial for reducing recurrence in complex cases. The aforementioned findings put forward significant insights for enhancing ERAT and advancing therapeutic outcomes.

Conference

UEG Week Berlin 2025

Topics

Colorectal

Submission format

Abstract

Session

Colorectal neoplasia: Risk, resection, outcomes (Posters)

Citation

United European Gastroenterology Journal 2025; 13 (Supplement 8)

Published

2025

More Like This:

The dynamic liver macrophage niche in health and disease: Lessons from using intravital microscopy

Moritz Peiseler

HELICOBACTER PYLORI CAGA PROMOTES GASTRIC EPITHELIAL CELL DNA DAMAGE THROUGH TRIM47-MEDIATED UBIQUITINATION AND DEGRADATION OF STAT1

Yin Zhu

PRECISION-CUT INTESTINAL SLICES PROVIDE EX VIVO ASSESSMENT OF REGION-SPECIFIC IMMUNE RESPONSES AND EFFICACY OF FILGOTINIB IN CROHN'S DISEASE

Katherina Sewald

NOT ALWAYS MECKEL’S: THE ROLE OF GASTRIC HETEROTOPIA IN GASTROINTESTINAL BLEEDING

Patrícia Vaz Conde

ASSESSMENT OF HISTOLOGIC ENDPOINTS AND PERFORMANCE IN THE TAK-062 PHASE 2 TRIAL

Daniel A. Leffler

A RARE CASE OF PSEUDOHEMATURIA INDUCED BY MESALAZINE

Helena Vasconcelos

UEG Presentation

Share via Email Share on Facebook Share on X Share on LinkedIn Share on Bluesky

The dynamic liver macrophage niche in health and disease: Lessons from using intravital microscopy

This content is part of Gutflix. Log in with your myUEG account, or create one free, to watch it.

Not sure what you can access? Learn more about account types.