UEG's content platform for gastroenterology education bringing recordings, courses, guidelines, and more together in one place.

UEG Week Berlin 2025 Recordings Gut Guide online What's new on Gutflix

Trending on Gutflix

Rate for better recommendations!

Your feedback helps us show you more of what you like and less of what you dislike!

More of this!

We will show you more similar content.

Not for me!

We won't suggest this again.

Bookmark!

Save this content for later!

New to myUEG? Create an account! Log In with myUEG account

UEG Poster

Audio / Video Poster

Share via Email Share on Facebook Share on X Share on LinkedIn Share on Bluesky

This content is part of Gutflix. Log in with your myUEG account, or create one free, to watch it.

Not sure what you can access? Learn more about account types.

ENDOSCOPIC TREATMENT FOR SUPERFICIAL LARYNGOPHARYNGEAL CANCER

Kenro Kawada 1, Hiroaki Kawabe 2, Kazuchika Ohno 2, Fujiwara Hisashi 1, Masayoshi Sakano 1, Unknown Unknown 1, Shigeo Haruki 1, Akihisa Tasaki 2, Takahiro Asakage 2

Affiliations

1 Tokyo Medical and Dental Univ., Bunkyoku, Tokyo, Japan

2 Tokyo Medical and Deantal University, Tokyo, Japan

Summary

AI Generated

Summary is not available for this content yet.

Download PDF

Was this helpful?

Thanks for your feedback.

This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

Abstract

Introduction

Recent improvements in endoscopic diagnostic techniques have made it possible to detect early-stage superficial laryngopharyngeal cancer, and endoscopic resection has become one of the standard treatments in Japan1). However, it is not fully known to what extent endoscopic treatment alone is curative.

Aims & Methods

To clarify the relationship between depth and lymph node metastasis in superficial laryngopharyngeal cancer. From August 1996 to April 2023, we experienced 501 cases of 810 lesions of superficial laryngopharyngeal cancer. Of these, 396 cases with 652 lesions (462 in the hypopharynx, 149 in the oropharynx, and 41 in the larynx) that were resected orally without prior treatment and followed for more than 1 year were included to investigate the relationship between depth and late lymph node metastasis.

Results

Endoscopic classification of the treated lesions was 81 lesions of type 0-Ⅰ(protruded type), 164 lesions of type 0-IIa(elevated type), 391 lesions of type 0-IIb(flat type), and 16 lesions of type 0-IIc (depressed type). Type 0-IIb was the most frequent.
Histopathologically evaluated 174 cases of intraepithelial carcinoma with 249 lesions showed no metastasis. On the other hand, of the 403 lesions in 295 cases of subepithelial invasive cancer (T1, tumor size less than 2cm: 213 lesions, T2, tumor size 2-4cm or smaller: 159 lesions, T3, tumor size greater than 4cm: 31 lesions), 30 lesions in 28 cases(9.5%) had later lymph node metastasis. Two of 305 lesions (0.65%) with tumor thickness less than 1000 μm were positive for metastasis. By size, 1 of 178 lesions in T1(0.6%), 1 of 111 lesions(0.9%) in T2, and 0 of 16 lesions in T3 were positive for metastasis. On the other hand, 28 of 98 lesions (28.6%) with tumor thickness greater than 1000 μm were positive for metastasis. By size, 6 of 35 lesions in T1(17.1%), 17 of 48 lesions(35.4%) in T2, and 5 of 15 lesions(33.3%) in T3 were positive for metastasis. The frequency of lymph node metastasis by endoscopic type was 20 of 81 lesions(24.7%) for type 0-I, 8 of 164 lesions (4.9%) for type 0-IIa, 1 of 391 lesions(0.25%) for type 0-IIb, and 1 of 16 lesions (6.25%) for type 0-IIc, metastasis was seen more frequently in type 0-I. The observation of brownish areas and brown dots with Image Enhanced Endoscopy is useful for detecting early-stage cancer. When examining the depth of the disease, the Valsalva method is recommended to focus on type 0-I lesions with a thickness of 1 mm or more and a well-stretched pharyngeal mucosa.

Conclusion

Superficial carcinomas with a thickness greater than 1 mm should be noted for late lymph node metastasis.

References

1) Watanabe A, Taniguchi M, Kimura Y, et al. Synopsis of transoral endoscopic laryngopharyngeal surgery for superficial pharyngeal cancers. Head Neck 2017; 39: 1779-1787

Disclosure

The authors have no financial conflicts of interest disclose concerning the study.

Conference

UEG Week Copenhagen 2023

Topics

Oesophagus

Submission format

Abstract

Session

PP 01 Oesophageal, gastric and duodenal disorders (Posters)

Citation

United European Gastroenterology Journal 2023; 11 (Supplement 8)

Published

2023

More Like This:

Pancreatic exocrine insufficiency

Miroslav Vujasinovic

A fusion-based deep-learning algorithm predicting PDAC metastasis from primary tumour

Núria Malats

ENDOSCOPIC DETECTION OF ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC) USING NOVEL FLUORESCENCE PROBE TARGETING DIPEPTIDYLPEPTIDASE IV (DPP-IV)

Yasuteru Urano

READMISSION WITHIN 30-DAYS OF COLONIC STENT PLACEMENT IS ASSOCIATED WITH INCREASED MORTALITY: A NATIONWIDE ANALYSIS OF OUTCOMES AND PREDICTORS OF READMISSION

Bhaumik Brahmbhatt

MACHINE LEARNING-DRIVEN PROGNOSTIC MODELING IN PANCREATIC DUCTAL ADENOCARCINOMA USING CLINICOPATHOLOGIC AND CAF EXPRESSION DATA

Adina Turcu-Stiolica

IMPACT OF TIME FROM DIAGNOSIS TO ENDOSCOPIC SUBMUCOSAL DISSECTION ON CURABILITY IN SUPERFICIAL ESOPHAGEAL SQUAMOUS CELL CARCINOMA

Daiki Sato

UEG Presentation

New

Share via Email Share on Facebook Share on X Share on LinkedIn Share on Bluesky

This content is part of Gutflix. Log in with your myUEG account, or create one free, to watch it.

Not sure what you can access? Learn more about account types.