The diagnosis and treatment of gastro-oesophageal reflux disease (GORD) have been driven by our knowledge of its pathophysiology. From equating GORD with oesophagitis and hiatal hernia to identifying the role of transient lower oesophageal sphincter relaxations, different GORD phenotypes and microscopic features, the pathophysiology is now understood to be multifactorial.

This online course covers the different components that contribute to the pathophysiology of GORD by following the path of the refluxate. The role of the stomach, antireflux barrier, refluxate, clearance mechanisms, mucosa and symptom perception are each considered in turn.  

Target audience

This course is suitable for gastroenterologists in training, but is also appropriate for physicians and surgeons in other disciplines, as well as nurses, biotechnicians and advanced-years’ medical students who have an interest in gastroenterology. 

Gastro-oesophageal reflux disease (GORD) is a highly prevalent condition that negatively impacts quality of life and confers considerable healthcare costs. Although various symptoms are associated with GORD, none are characteristic for diagnosis of the disease.

This online course covers needs in the diagnosis of GORD, symptoms and questionnaires, the PPI test, endoscopy and biopsies, reflux monitoring, oesophageal manometry, barium studies and other biomarkers. Conclusive, inconclusive and paediatric GORD are also considered. 

Target audience

This course is suitable for gastroenterologists in training and physicians and surgeons in other disciplines, as well as nurses, biotechnicians and advanced-years’ medical students who have an interest in gastroenterology.