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Mistakes in rumination syndrome and how to avoid them

Alberto Ezquerra-Durán, Elizabeth Barba Orozco

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Summary is not available for this content yet.

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This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

References

Mistakes
References
Mistake 1 Mistake 2 Mistake 3 Mistake 4 Mistake 5 Mistake 6 Mistake 7
1.
Brockbank EM. Merycism or rumination in man. Br Med J. 1907;1:421–427. [Link]
2.
Malagelada C, Keller J, Sifrim D, et al. European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management. United European Gastroenterol J. Published online 2025:1-45. [Link]
3.
Stanghellini V, Chan FKL, Hasler WL, et al. Gastroduodenal Disorders. Gastroenterology. 2016;150(6):1380-1392. [Link]
4.
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 5th Edn. 2013th ed. (American Psychiatric Association, ed.). [Link]
5.
Burri E, Cisternas D, Villoria A, et al. Accommodation of the abdomen to its content: integrated abdomino‐thoracic response. Neurogastroenterology & Motility. 2012;24(4):312. [Link]
6.
Barba E, Burri E, Accarino A, et al. Biofeedback-Guided Control of Abdominothoracic Muscular Activity Reduces Regurgitation Episodes in Patients With Rumination. Clinical Gastroenterology and Hepatology. 2015;13(1):100-106.e1. [Link]
7.
Haworth JJ, Treadway S, Hobson AR. The prevalence of rumination syndrome and rumination disorder: A systematic review and meta‐analysis. Neurogastroenterology & Motility. 2024;36(7):1-9. [Link]
8.
O’Brien MD, Bruce BK, Camilleri M. The rumination syndrome: Clinical features rather than manometric diagnosis. Gastroenterology. 1995;108(4):1024-1029. [Link]
9.
Chial HJ, Camilleri M, Williams DE, Litzinger K, Perrault J. Rumination Syndrome in Children and Adolescents: Diagnosis, Treatment, and Prognosis. Pediatrics. 2003;111(1):158-162. [Link]
10.
Halland M, Pandolfino J, Barba E. Diagnosis and Treatment of Rumination Syndrome. Clinical Gastroenterology and Hepatology. 2018;16(10):1549-1555. [Link]
11.
Benninga MA, Nurko S, Faure C, Hyman PE, St. James Roberts I, Schechter NL. Childhood Functional Gastrointestinal Disorders: Neonate/Toddler. Gastroenterology. 2016;150(6):1443-1455.e2. [Link]
12.
Josefsson A, Hreinsson JP, Simrén M, et al. Global Prevalence and Impact of Rumination Syndrome. Gastroenterology. 2022;162(3):731-742.e9. [Link]
13.
Treasure J, Duarte TA, Schmidt U. Eating disorders. The Lancet. 2020;395(10227):899-911. [Link]
14.
Vijayvargiya P, Iturrino J, Camilleri M, et al. Novel association of rectal evacuation disorder and rumination syndrome: Diagnosis, comorbidities, and treatment. United European Gastroenterology Journal. 2014;2(1):38-46. [Link]
15.
Cai JX, Wong D, Lee DJH, Chan WW. Eating and Psychiatric Disorders Are Independent Risk Factors for Rumination Syndrome. Journal of Clinical Gastroenterology. 2022;56(3):228-233. [Link]
16.
Hartmann AS, Zenger M, Glaesmer H, et al. Prevalence of pica and rumination behaviours in adults and associations with eating disorder and general psychopathology: findings form a population-based study. Epidemiology and Psychiatric Sciences. 2022;31:e40. [Link]
17.
Remes-Troche JM, Cid-Juárez S, Campos-Ramos I, et al. Role of physical, psychological and sexual abuse in functional digestive disorders. A case-controls trial. Revista de gastroenterologia de Mexico. 2008;73(4):209-216. [Link]
18.
Zerbib F, Bredenoord AJ, Fass R, et al. ESNM/ANMS consensus paper: Diagnosis and management of refractory gastro‐esophageal reflux disease. Neurogastroenterology & Motility. 2021;33(4):1-25. [Link]
19.
Yadlapati R, Tye M, Roman S, Kahrilas PJ, Ritter K, Pandolfino JE. Postprandial High-Resolution Impedance Manometry Identifies Mechanisms of Nonresponse to Proton Pump Inhibitors. Clinical Gastroenterology and Hepatology. 2018;16(2):211-218.e1. [Link]
20.
Nakagawa K, Sawada A, Hoshikawa Y, et al. Persistent Postprandial Regurgitation vs Rumination in Patients With Refractory Gastroesophageal Reflux Disease Symptoms: Identification of a Distinct Rumination Pattern Using Ambulatory Impedance-pH Monitoring. American Journal of Gastroenterology. 2019;114(8):1248-1255. [Link]
21.
Sawada A, Guzman M, Nikaki K, et al. Identification of Different Phenotypes of Esophageal Reflux Hypersensitivity and Implications for Treatment. Clinical Gastroenterology and Hepatology. 2021;19(4):690-698.e2. [Link]
22.
Lacy BE, Parkman HP, Camilleri M. Chronic nausea and vomiting: evaluation and treatment. American Journal of Gastroenterology. 2018;113(5):647-659. [Link]
23.
Malik R, Srivastava A, Yachha SK, Poddar U. Chronic vomiting in children: A prospective study reveals rumination syndrome is an important etiology that is underdiagnosed and untreated. Indian Journal of Gastroenterology. 2020;39(2):196-203. [Link]
24.
Murray HB, Pasricha TS, Jehangir A, Thomas JJ, Kuo B, Parkman HP. Detection and characteristics of rumination syndrome in patients presenting for gastric symptom evaluation. Neurogastroenterology & Motility. 2021;33(8):1-8. [Link]
25.
Bredenoord AJ, Chial HJ, Camilleri M, Mullan BP, Murray JA. Gastric accommodation and emptying in evaluation of patients with upper gastrointestinal symptoms. Clinical Gastroenterology and Hepatology. 2003;1(4):264-272. [Link]
26.
Zand Irani M, Jones MP, Halland M, et al. Prevalence, symptoms and risk factor profile of rumination syndrome and functional dyspepsia: a population‐based study. Aliment Pharmacol Ther. 2021;54(11-12):1416-1431. [Link]
27.
Kindt S, Tack J. Impaired gastric accommodation and its role in dyspepsia. Gut. 2006;55(12):1685-1691. [Link]
28.
Thumshirn M, Camilleri M, Hanson RB, Williams DE, Schei AJ, Kammer PP. Gastric mechanosensory and lower esophageal sphincter function in rumination syndrome. American Journal of Physiology-Gastrointestinal and Liver Physiology. 1998;275(2):G314-G321. [Link]
29.
Hoshikawa Y, Fitzke H, Sweis R, et al. Rumination syndrome: Assessment of vagal tone during and after meals and during diaphragmatic breathing. Neurogastroenterology & Motility. 2020;32(11):1-9. [Link]
30.
Halland M, Talley NJ, Jones M, Murray JA, Cameron R, Walker MM. Duodenal Pathology in Patients with Rumination Syndrome: Duodenal Eosinophilia and Increased Intraepithelial Lymphocytes. Digestive Diseases and Sciences. 2019;64(3):832-837. [Link]
31.
Zand Irani M, Eslick GD, Brown G, Talley NJ. Letter: eosinophilic duodenitis and increased intraepithelial lymphocytes in rumination syndrome – more evidence. Alimentary Pharmacology & Therapeutics. 2023;57(11):1353-1354. [Link]
32.
Friesen HJ, Rosen J, Low Kapalu C, et al. Mucosal eosinophils, mast cells, and intraepithelial lymphocytes in youth with rumination syndrome. Neurogastroenterology & Motility. 2021;33(10):1-6. [Link]
33.
Rajindrajith S, Devanarayana NM, Crispus Perera BJ. Rumination syndrome in children and adolescents: a school survey assessing prevalence and symptomatology. BMC Gastroenterology. 2012;12(1):163. [Link]
34.
Barba E, Accarino A, Soldevilla A, Malagelada JR, Azpiroz F. Randomized, Placebo-Controlled Trial of Biofeedback for the Treatment of Rumination. American Journal of Gastroenterology. 2016;111(7):1007-1013. [Link]
35.
Monagas J, Ritwik P, Kolomensky A, et al. Rumination Syndrome and Dental Erosions in Children. Journal of Pediatric Gastroenterology and Nutrition. 2017;64(6):930-932. [Link]
36.
Levine DF, Wingate DL, Pfeffer JM, Butcher P. Habitual rumination: a benign disorder. BMJ. 1983;287(6387):255-256. [Link]
37.
Murray HB, Juarascio AS, Di Lorenzo C, Drossman DA, Thomas JJ. Diagnosis and Treatment of Rumination Syndrome: A Critical Review. American Journal of Gastroenterology. 2019;114(4):562-578. [Link]
38.
Tucker E, Knowles K, Wright J, Fox MR. Rumination variations: aetiology and classification of abnormal behavioural responses to digestive symptoms based on high‐resolution manometry studies. Alimentary Pharmacology & Therapeutics. 2013;37(2):263-274. [Link]
39.
Kessing BF, Bredenoord AJ, Smout AJPM. Objective Manometric Criteria for the Rumination Syndrome. American Journal of Gastroenterology. 2014;109(1):52-59. [Link]
40.
Geysen H, Michielsen S, Rommel N, Vanuytsel T, Tack J, Pauwels A. The gastro‐sphincteric pressure gradient: A new parameter to diagnose a rumination episode. Neurogastroenterology & Motility. 2021;33(6):1-7. [Link]
41.
Nakagawa K, Sawada A, Hoshikawa Y, et al. Persistent Postprandial Regurgitation vs Rumination in Patients With Refractory Gastroesophageal Reflux Disease Symptoms: Identification of a Distinct Rumination Pattern Using Ambulatory Impedance-pH Monitoring. American Journal of Gastroenterology. 2019;114(8):1248-1255. [Link]
42.
Barba E, Burri E, Accarino A, et al. Biofeedback-guided control of abdominothoracic muscular activity reduces regurgitation episodes in patients with rumination. Clinical Gastroenterology and Hepatology. 2015;13(1):100-106.e1. [Link]
43.
Halland M, Parthasarathy G, Bharucha AE, Katzka DA. Diaphragmatic breathing for rumination syndrome: efficacy and mechanisms of action. Neurogastroenterology & Motility. 2016;28(3):384-391. [Link]
44.
Murray HB, Zhang F, Call CC, et al. Comprehensive Cognitive-Behavioral Interventions Augment Diaphragmatic Breathing for Rumination Syndrome: A Proof-of-Concept Trial. Digestive Diseases and Sciences. 2021;66(10):3461-3469. [Link]
45.
Pauwels A, Broers C, Van Houtte B, Rommel N, Vanuytsel T, Tack J. A Randomized Double-Blind, Placebo-Controlled, Cross-Over Study Using Baclofen in the Treatment of Rumination Syndrome. American Journal of Gastroenterology. 2018;113(1):97-104. [Link]
46.
Drossman DA, Tack J, Ford AC, Szigethy E, Törnblom H, Van Oudenhove L. Neuromodulators for Functional Gastrointestinal Disorders (Disorders of Gut−Brain Interaction): A Rome Foundation Working Team Report. Gastroenterology. 2018;154(4):1140-1171.e1. [Link]
47.
Robles A, Romero YA, Tatro E, Quezada H, McCallum RW. Outcomes of Treating Rumination Syndrome with a Tricyclic Antidepressant and Diaphragmatic Breathing. The American Journal of the Medical Sciences. 2020;360(1):42-49. [Link]

Abstract

Topics

Neurogastroenterology & Motility

Citation

Ezquerra-Durán A and Barba-Orozco E. Mistakes in rumination syndrome and how to avoid them. UEG Education 2025; 25: 10-13.

Published

2025

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MASLD with Sven Francque - Part 2

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Summary

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Summary is not available for this content yet.

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This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

Abstract

Topics

Hepatobiliary

Published

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Share via Email Share on Facebook Share on X Share on LinkedIn Share on Bluesky

Log in to continue.

This content is part of Gutflix. Log in with your myUEG account, or create one free, to watch it.

Log In Create a free account

Not sure what you can access? Learn more about account types.

Mistakes in Familial Mediterranean Fever and how to avoid them

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Summary

AI Generated

Summary is not available for this content yet.

Download PDF

Was this helpful?

Thanks for your feedback.

This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

References

Mistakes
References
Mistake 1 Mistake 2 Mistake 3 Mistake 4 Mistake 5 Mistake 6 Mistake 7
1.
Brockbank EM. Merycism or rumination in man. Br Med J. 1907;1:421–427. [Link]
2.
Malagelada C, Keller J, Sifrim D, et al. European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management. United European Gastroenterol J. Published online 2025:1-45. [Link]
3.
Stanghellini V, Chan FKL, Hasler WL, et al. Gastroduodenal Disorders. Gastroenterology. 2016;150(6):1380-1392. [Link]
4.
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 5th Edn. 2013th ed. (American Psychiatric Association, ed.). [Link]
5.
Burri E, Cisternas D, Villoria A, et al. Accommodation of the abdomen to its content: integrated abdomino‐thoracic response. Neurogastroenterology & Motility. 2012;24(4):312. [Link]
6.
Barba E, Burri E, Accarino A, et al. Biofeedback-Guided Control of Abdominothoracic Muscular Activity Reduces Regurgitation Episodes in Patients With Rumination. Clinical Gastroenterology and Hepatology. 2015;13(1):100-106.e1. [Link]
7.
Haworth JJ, Treadway S, Hobson AR. The prevalence of rumination syndrome and rumination disorder: A systematic review and meta‐analysis. Neurogastroenterology & Motility. 2024;36(7):1-9. [Link]
8.
O’Brien MD, Bruce BK, Camilleri M. The rumination syndrome: Clinical features rather than manometric diagnosis. Gastroenterology. 1995;108(4):1024-1029. [Link]
9.
Chial HJ, Camilleri M, Williams DE, Litzinger K, Perrault J. Rumination Syndrome in Children and Adolescents: Diagnosis, Treatment, and Prognosis. Pediatrics. 2003;111(1):158-162. [Link]
10.
Halland M, Pandolfino J, Barba E. Diagnosis and Treatment of Rumination Syndrome. Clinical Gastroenterology and Hepatology. 2018;16(10):1549-1555. [Link]
11.
Benninga MA, Nurko S, Faure C, Hyman PE, St. James Roberts I, Schechter NL. Childhood Functional Gastrointestinal Disorders: Neonate/Toddler. Gastroenterology. 2016;150(6):1443-1455.e2. [Link]
12.
Josefsson A, Hreinsson JP, Simrén M, et al. Global Prevalence and Impact of Rumination Syndrome. Gastroenterology. 2022;162(3):731-742.e9. [Link]
13.
Treasure J, Duarte TA, Schmidt U. Eating disorders. The Lancet. 2020;395(10227):899-911. [Link]
14.
Vijayvargiya P, Iturrino J, Camilleri M, et al. Novel association of rectal evacuation disorder and rumination syndrome: Diagnosis, comorbidities, and treatment. United European Gastroenterology Journal. 2014;2(1):38-46. [Link]
15.
Cai JX, Wong D, Lee DJH, Chan WW. Eating and Psychiatric Disorders Are Independent Risk Factors for Rumination Syndrome. Journal of Clinical Gastroenterology. 2022;56(3):228-233. [Link]
16.
Hartmann AS, Zenger M, Glaesmer H, et al. Prevalence of pica and rumination behaviours in adults and associations with eating disorder and general psychopathology: findings form a population-based study. Epidemiology and Psychiatric Sciences. 2022;31:e40. [Link]
17.
Remes-Troche JM, Cid-Juárez S, Campos-Ramos I, et al. Role of physical, psychological and sexual abuse in functional digestive disorders. A case-controls trial. Revista de gastroenterologia de Mexico. 2008;73(4):209-216. [Link]
18.
Zerbib F, Bredenoord AJ, Fass R, et al. ESNM/ANMS consensus paper: Diagnosis and management of refractory gastro‐esophageal reflux disease. Neurogastroenterology & Motility. 2021;33(4):1-25. [Link]
19.
Yadlapati R, Tye M, Roman S, Kahrilas PJ, Ritter K, Pandolfino JE. Postprandial High-Resolution Impedance Manometry Identifies Mechanisms of Nonresponse to Proton Pump Inhibitors. Clinical Gastroenterology and Hepatology. 2018;16(2):211-218.e1. [Link]
20.
Nakagawa K, Sawada A, Hoshikawa Y, et al. Persistent Postprandial Regurgitation vs Rumination in Patients With Refractory Gastroesophageal Reflux Disease Symptoms: Identification of a Distinct Rumination Pattern Using Ambulatory Impedance-pH Monitoring. American Journal of Gastroenterology. 2019;114(8):1248-1255. [Link]
21.
Sawada A, Guzman M, Nikaki K, et al. Identification of Different Phenotypes of Esophageal Reflux Hypersensitivity and Implications for Treatment. Clinical Gastroenterology and Hepatology. 2021;19(4):690-698.e2. [Link]
22.
Lacy BE, Parkman HP, Camilleri M. Chronic nausea and vomiting: evaluation and treatment. American Journal of Gastroenterology. 2018;113(5):647-659. [Link]
23.
Malik R, Srivastava A, Yachha SK, Poddar U. Chronic vomiting in children: A prospective study reveals rumination syndrome is an important etiology that is underdiagnosed and untreated. Indian Journal of Gastroenterology. 2020;39(2):196-203. [Link]
24.
Murray HB, Pasricha TS, Jehangir A, Thomas JJ, Kuo B, Parkman HP. Detection and characteristics of rumination syndrome in patients presenting for gastric symptom evaluation. Neurogastroenterology & Motility. 2021;33(8):1-8. [Link]
25.
Bredenoord AJ, Chial HJ, Camilleri M, Mullan BP, Murray JA. Gastric accommodation and emptying in evaluation of patients with upper gastrointestinal symptoms. Clinical Gastroenterology and Hepatology. 2003;1(4):264-272. [Link]
26.
Zand Irani M, Jones MP, Halland M, et al. Prevalence, symptoms and risk factor profile of rumination syndrome and functional dyspepsia: a population‐based study. Aliment Pharmacol Ther. 2021;54(11-12):1416-1431. [Link]
27.
Kindt S, Tack J. Impaired gastric accommodation and its role in dyspepsia. Gut. 2006;55(12):1685-1691. [Link]
28.
Thumshirn M, Camilleri M, Hanson RB, Williams DE, Schei AJ, Kammer PP. Gastric mechanosensory and lower esophageal sphincter function in rumination syndrome. American Journal of Physiology-Gastrointestinal and Liver Physiology. 1998;275(2):G314-G321. [Link]
29.
Hoshikawa Y, Fitzke H, Sweis R, et al. Rumination syndrome: Assessment of vagal tone during and after meals and during diaphragmatic breathing. Neurogastroenterology & Motility. 2020;32(11):1-9. [Link]
30.
Halland M, Talley NJ, Jones M, Murray JA, Cameron R, Walker MM. Duodenal Pathology in Patients with Rumination Syndrome: Duodenal Eosinophilia and Increased Intraepithelial Lymphocytes. Digestive Diseases and Sciences. 2019;64(3):832-837. [Link]
31.
Zand Irani M, Eslick GD, Brown G, Talley NJ. Letter: eosinophilic duodenitis and increased intraepithelial lymphocytes in rumination syndrome – more evidence. Alimentary Pharmacology & Therapeutics. 2023;57(11):1353-1354. [Link]
32.
Friesen HJ, Rosen J, Low Kapalu C, et al. Mucosal eosinophils, mast cells, and intraepithelial lymphocytes in youth with rumination syndrome. Neurogastroenterology & Motility. 2021;33(10):1-6. [Link]
33.
Rajindrajith S, Devanarayana NM, Crispus Perera BJ. Rumination syndrome in children and adolescents: a school survey assessing prevalence and symptomatology. BMC Gastroenterology. 2012;12(1):163. [Link]
34.
Barba E, Accarino A, Soldevilla A, Malagelada JR, Azpiroz F. Randomized, Placebo-Controlled Trial of Biofeedback for the Treatment of Rumination. American Journal of Gastroenterology. 2016;111(7):1007-1013. [Link]
35.
Monagas J, Ritwik P, Kolomensky A, et al. Rumination Syndrome and Dental Erosions in Children. Journal of Pediatric Gastroenterology and Nutrition. 2017;64(6):930-932. [Link]
36.
Levine DF, Wingate DL, Pfeffer JM, Butcher P. Habitual rumination: a benign disorder. BMJ. 1983;287(6387):255-256. [Link]
37.
Murray HB, Juarascio AS, Di Lorenzo C, Drossman DA, Thomas JJ. Diagnosis and Treatment of Rumination Syndrome: A Critical Review. American Journal of Gastroenterology. 2019;114(4):562-578. [Link]
38.
Tucker E, Knowles K, Wright J, Fox MR. Rumination variations: aetiology and classification of abnormal behavioural responses to digestive symptoms based on high‐resolution manometry studies. Alimentary Pharmacology & Therapeutics. 2013;37(2):263-274. [Link]
39.
Kessing BF, Bredenoord AJ, Smout AJPM. Objective Manometric Criteria for the Rumination Syndrome. American Journal of Gastroenterology. 2014;109(1):52-59. [Link]
40.
Geysen H, Michielsen S, Rommel N, Vanuytsel T, Tack J, Pauwels A. The gastro‐sphincteric pressure gradient: A new parameter to diagnose a rumination episode. Neurogastroenterology & Motility. 2021;33(6):1-7. [Link]
41.
Nakagawa K, Sawada A, Hoshikawa Y, et al. Persistent Postprandial Regurgitation vs Rumination in Patients With Refractory Gastroesophageal Reflux Disease Symptoms: Identification of a Distinct Rumination Pattern Using Ambulatory Impedance-pH Monitoring. American Journal of Gastroenterology. 2019;114(8):1248-1255. [Link]
42.
Barba E, Burri E, Accarino A, et al. Biofeedback-guided control of abdominothoracic muscular activity reduces regurgitation episodes in patients with rumination. Clinical Gastroenterology and Hepatology. 2015;13(1):100-106.e1. [Link]
43.
Halland M, Parthasarathy G, Bharucha AE, Katzka DA. Diaphragmatic breathing for rumination syndrome: efficacy and mechanisms of action. Neurogastroenterology & Motility. 2016;28(3):384-391. [Link]
44.
Murray HB, Zhang F, Call CC, et al. Comprehensive Cognitive-Behavioral Interventions Augment Diaphragmatic Breathing for Rumination Syndrome: A Proof-of-Concept Trial. Digestive Diseases and Sciences. 2021;66(10):3461-3469. [Link]
45.
Pauwels A, Broers C, Van Houtte B, Rommel N, Vanuytsel T, Tack J. A Randomized Double-Blind, Placebo-Controlled, Cross-Over Study Using Baclofen in the Treatment of Rumination Syndrome. American Journal of Gastroenterology. 2018;113(1):97-104. [Link]
46.
Drossman DA, Tack J, Ford AC, Szigethy E, Törnblom H, Van Oudenhove L. Neuromodulators for Functional Gastrointestinal Disorders (Disorders of Gut−Brain Interaction): A Rome Foundation Working Team Report. Gastroenterology. 2018;154(4):1140-1171.e1. [Link]
47.
Robles A, Romero YA, Tatro E, Quezada H, McCallum RW. Outcomes of Treating Rumination Syndrome with a Tricyclic Antidepressant and Diaphragmatic Breathing. The American Journal of the Medical Sciences. 2020;360(1):42-49. [Link]

Abstract

Familial Mediterranean fever (FMF), also called periodic disease, Armenian disease, etc., is a prototypical autoinflammatory disorder where the underlying mechanism is the dysfunction of innate immunity, resulting in unprovoked episodes of inflammation.1 Although considered rare worldwide, it is prevalent in people of Mediterranean origin; however, one can expect to encounter patients in all parts of the modern world. FMF is a monogenic disease with autosomal recessive inheritance.2 Unlike other monogenic disorders, the diagnosis remains largely clinical, and it is important to understand the limitations of genetic testing. Another distinguishing feature is the well-established effectiveness of lifelong monotherapy with colchicine in preventing attacks and complications.3

Topics

Primary Care

Published

2025

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Share via Email Share on Facebook Share on X Share on LinkedIn Share on Bluesky

Log in to continue.

This content is part of Gutflix. Log in with your myUEG account, or create one free, to watch it.

Log In Create a free account

Not sure what you can access? Learn more about account types.

Complications in endoscopy with Srisha Hebbar Part 1

Srisha Hebbar, Pradeep Mundre

Summary

AI Generated

Summary is not available for this content yet.

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Endoscopy

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2025

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UEG Mistakes In Articles
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Mistakes in hepatitis C and how to avoid them

Ana Catarina Garcia, Gonçalo Alexandrino

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References

Mistakes
References
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41.
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42.
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43.
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Abstract

Hepatitis C virus (HCV) infection remains an important global health concern. It is estimated that there are approximately 50 million people infected with HCV globally, with around 1 million new infections each year and about 242,000 deaths annually attributed to HCV-related complications. Most acute HCV infections (55–85%) become chronic due to the virus’s effective evasion strategies, with spontaneous clearance being rare once chronicity is established. This condition often progresses silently, with many individuals unaware of their infection until advanced liver damage has occurred. If left untreated, HCV can lead to severe complications, including liver cirrhosis and hepatocellular carcinoma (HCC). HCV transmission occurs mainly through percutaneous exposure to infected blood. HCV can also spread from mother to infant (vertical transmission) and, less frequently, via sexual contact.1,2 In recent years, the introduction of oral direct-acting antivirals (DAAs), with remarkable safety and effectiveness profiles, has led to a sustained virological response (SVR) in virtually all (>97%) HCV-infected patients, regardless of HCV genotype or disease stage. However, significant barriers remain, such as issues with diagnosis, access to treatment and awareness of the disease.

Here, we discuss some of the misconceptions in HCV management and provide a practical management approach grounded in evidence and clinical experience.

Topics

Hepatobiliary

Citation

Garcia A.C and Alexandrino G. Mistakes in hepatits C and how to avoid them. UEG Education 2025; 25: 14-17.

Published

2025

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Summary

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This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

Abstract

Topics

Oesophagus

Published

2026

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Summary

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This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

Abstract

Published

2025

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