UEG Week Recordings UEG Week Posters Online courses Guidelines Mistakes in... Podcasts Webinars
new
Gut Guide online
Visit ueg.eu Create myUEG account Log In
Visit ueg.eu Create myUEG account Log In

Filters:

UEG Mistakes In Articles
Share via Email Share on Facebook Share on X Share on LinkedIn Share on Bluesky

Log in to continue.

This content is part of Gutflix. Log in with your myUEG account, or create one free, to watch it.

Log In Create a free account

Not sure what you can access? Learn more about account types.

Mistakes in endoscopy and how to avoid them

Jacques Deviere, Arnaud Lemmers

Summary

AI Generated

This material discusses diagnostic and therapeutic endoscopic mistakes based on clinical experience and proposes evidence-based approaches to avoid them.

  • Upper and lower gastrointestinal endoscopy are performed daily for nonspecific indications such as heartburn, pain, anaemia, bleeding, and workup of portal hypertension.
  • Some patients undergo multiple diagnostic endoscopic procedures over months with nonconclusive findings.
  • Diagnostic mistakes based on the authors' endoscopic experience are discussed using an evidence-based approach.
  • For therapeutic procedures like ERCP and resections, important mistakes often seen in practice with major patient consequences are presented, along with simple approaches to avoid them.
Download PDF

Was this helpful?

Thanks for your feedback.

This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

References

Mistakes
References
Mistake 1 Mistake 2 Mistake 3 Mistake 4 Mistake 5 Mistake 6 Mistake 7 Mistake 8
1.
Cameron AJ, Higgins JA. Linear gastric erosion. A lesion associated with large diaphragmatic hernia and chronic blood loss anemia. Gastroenterology. 1986; 91: 338–342. [Link]
2.
Camus M, et al. Severe upper gastrointestinal hemorrhage from linear gastric ulcers in large hiatal hernias: a large prospective case series of Cameron ulcers. Endoscopy 2013; 45: 397–400. [Link]
3.
Shin HJ, et al. Risk factors for Dieulafoy lesions in the upper gastrointestinal tract. Clin Endosc 2015; 48: 228–233. [Link]
4.
Lara LF, et al. Dieulafoy lesions of the GI tract: localization and therapeutic outcomes. Dig Dis Sci 2010; 55: 3436–3441. [Link]
5.
Baxter M and Aly EH. Dieulafoy's lesion: current trends in diagnosis and management. Ann R Coll Surg Engl 2010; 92: 548–554. [Link]
6.
Jeon HK and Kim GH. Endoscopic management of Dieulafoy's lesion. Clin Endosc 2015; 48: 112–120. [Link]
7.
Hirano I. 2015 David Y Graham Lecture: The first two decades of eosinophilic esophagitis—from acid reflux to food allergy. Am J Gastro 2016; 111: 770–776. [Link]
8.
Spechler SJ, et al. American Gastroenterological Association technical review on the management of Barrett's esophagus. Gastroenterology 2011; 140: e18–e13. [Link]
9.
Vahabzadeh B, et al. Validation of the Prague C and M criteria for the endoscopic grading of Barrett’s esophagus by gastroenterology trainees: a multicenter study. Gastrointest Endosc 2012; 75: 236–241. [Link]
10.
Patwardhan VR and Cardenas A. Review article: the management of portal hypertensive gastropathy and gastric antral vascular ectasia in cirrhosis. Aliment Pharmacol Ther 2014; 40: 354–362. [Link]
11.
Lemmers A, et al. Gastrointestinal polypoid lesions: a poorly known endoscopic feature of portal hypertension. United European Gastroenterol J. 2014; 2: 189–196. [Link]
12.
Pimentel-Nunes P, et al. Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guidelines. Endoscopy 2015; 47: 829–854. [Link]
13.
Moss A, et al. Long-term adenomare currence following wide-field endoscopic mucosal resection (WF-EMR) for advanced colonic mucosal neoplasia is infrequent: results and risk factors in 1000 cases from the Australian Colonic EMR (ACE) study. Gut 2015; 64: 57–65. [Link]
14.
Dumonceau JM, et al. Biliary stenting: indications, choice of stents and results: European Society of Gastrointestinal Endoscopy (ESGE) clinical guideline. Endoscopy 2012; 44: 277–298. [Link]
15.
Albert J, et al. Anatomy of the biliary and pancreatic ducts. In Endoscopy retrograde cholangiopancreatography (ERCP)—Current practice and future perspectives. Uni-Med Verlag AG, 2015; pp.25–27.
16.
The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002. Gastrointest Endosc 2003; 58: S3–43. [Link]
17.
Rugge M, et al. Gastritis staging in clinical practice: the OLGA staging system. Gut 2007; 56: 631–636. [Link]
18.
Hayee B, et al. Magnification narrow-band imaging for the diagnosis of early gastric cancer: a review of the Japanese literature for the Western endoscopist. Gastrointest Endosc 2013; 78: 452–461. [Link]
19.
Hayashi N, et al. Endoscopic prediction of deep submucosal invasive carcinoma: validation of the narrow-band imaging international colorectal endoscopic (NICE) classification. Gastrointest Endosc 2013; 78: 625–632. [Link]
20.
Kudo S, et al. Diagnosis of colorectal tumorous lesions by magnifying endoscopy. Gastrointest Endosc 1996; 44: 8–14. [Link]
21.
Bouchard S and Devière J. endoscopic treatment for complex biliary and pancreatic duct injuries. Journal of Digestive Endoscopy 2014; 5: 2–12. [Link]
22.
Bouchard S, et al. Su1598 Endoscopic or combined endoscopic/percutaneous management of patients with complex bile duct injuries and biliary exclusion. Gastrointest Endosc 2015; 81 (Supplement): AB345–AB346. [Link]

Abstract

Upper and lower gastrointestinal endoscopy examinations are performed daily as routine diagnostic procedures in a large number of patients with nonspecific indications, such as heartburn, pain, anaemia, bleeding, workup of portal hypertension and so on. Most of the examinations will point to a classic diagnosis (e.g. peptic disease, cancer, variceal management), but sometimes we see patients who've had multiple diagnostic endoscopic procedures in the previous few months with nonconclusive findings. The diagnostic mistakes discussed here are those that sprang to mind based on our endoscopic experience and they are discussed in an evidence-based approach. For therapeutic endoscopic procedures (e.g. ERCP and resections), we present the most important mistakes that are often seen in our practice and have major consequences for the patient. We propose, from our experience, a simple approach to avoid these mistakes.

Topics

Endoscopy

Published

2024

More Like This:

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Christos Triantos Christos Triantos, Ioannis Elefsiniotis, Spyridon Pantzios

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

Henit Yanai Henit Yanai

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

Sanjay Pandanaboyana Sanjay Pandanaboyana

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

Laura Leeuwenburgh Laura Leeuwenburgh

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Egle Dieninyte - Misiune Egle Dieninyte - Misiune, Giuseppe Vanella

Episode 9: Harmonising Gastroenterology Training Across Europe

Episode 9: Harmonising Gastroenterology Training Across Europe

Mohsan Subhani Mohsan Subhani, Sophie Schlosser-Hupf, Henriette Heinrich

UEG Mistakes In Articles
New
Share via Email Share on Facebook Share on X Share on LinkedIn Share on Bluesky

Log in to continue.

This content is part of Gutflix. Log in with your myUEG account, or create one free, to watch it.

Log In Create a free account

Not sure what you can access? Learn more about account types.

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Spyridon Pantzios, Ioannis Elefsiniotis, Christos Triantos

Summary

AI Generated

Summary is not available for this content yet.

Download PDF

Was this helpful?

Thanks for your feedback.

This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

References

Mistakes
References
Mistake 1 Mistake 2 Mistake 3 Mistake 4 Mistake 5 Mistake 6 Mistake 7 Mistake 8
1.
Cameron AJ, Higgins JA. Linear gastric erosion. A lesion associated with large diaphragmatic hernia and chronic blood loss anemia. Gastroenterology. 1986; 91: 338–342. [Link]
2.
Camus M, et al. Severe upper gastrointestinal hemorrhage from linear gastric ulcers in large hiatal hernias: a large prospective case series of Cameron ulcers. Endoscopy 2013; 45: 397–400. [Link]
3.
Shin HJ, et al. Risk factors for Dieulafoy lesions in the upper gastrointestinal tract. Clin Endosc 2015; 48: 228–233. [Link]
4.
Lara LF, et al. Dieulafoy lesions of the GI tract: localization and therapeutic outcomes. Dig Dis Sci 2010; 55: 3436–3441. [Link]
5.
Baxter M and Aly EH. Dieulafoy's lesion: current trends in diagnosis and management. Ann R Coll Surg Engl 2010; 92: 548–554. [Link]
6.
Jeon HK and Kim GH. Endoscopic management of Dieulafoy's lesion. Clin Endosc 2015; 48: 112–120. [Link]
7.
Hirano I. 2015 David Y Graham Lecture: The first two decades of eosinophilic esophagitis—from acid reflux to food allergy. Am J Gastro 2016; 111: 770–776. [Link]
8.
Spechler SJ, et al. American Gastroenterological Association technical review on the management of Barrett's esophagus. Gastroenterology 2011; 140: e18–e13. [Link]
9.
Vahabzadeh B, et al. Validation of the Prague C and M criteria for the endoscopic grading of Barrett’s esophagus by gastroenterology trainees: a multicenter study. Gastrointest Endosc 2012; 75: 236–241. [Link]
10.
Patwardhan VR and Cardenas A. Review article: the management of portal hypertensive gastropathy and gastric antral vascular ectasia in cirrhosis. Aliment Pharmacol Ther 2014; 40: 354–362. [Link]
11.
Lemmers A, et al. Gastrointestinal polypoid lesions: a poorly known endoscopic feature of portal hypertension. United European Gastroenterol J. 2014; 2: 189–196. [Link]
12.
Pimentel-Nunes P, et al. Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guidelines. Endoscopy 2015; 47: 829–854. [Link]
13.
Moss A, et al. Long-term adenomare currence following wide-field endoscopic mucosal resection (WF-EMR) for advanced colonic mucosal neoplasia is infrequent: results and risk factors in 1000 cases from the Australian Colonic EMR (ACE) study. Gut 2015; 64: 57–65. [Link]
14.
Dumonceau JM, et al. Biliary stenting: indications, choice of stents and results: European Society of Gastrointestinal Endoscopy (ESGE) clinical guideline. Endoscopy 2012; 44: 277–298. [Link]
15.
Albert J, et al. Anatomy of the biliary and pancreatic ducts. In Endoscopy retrograde cholangiopancreatography (ERCP)—Current practice and future perspectives. Uni-Med Verlag AG, 2015; pp.25–27.
16.
The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002. Gastrointest Endosc 2003; 58: S3–43. [Link]
17.
Rugge M, et al. Gastritis staging in clinical practice: the OLGA staging system. Gut 2007; 56: 631–636. [Link]
18.
Hayee B, et al. Magnification narrow-band imaging for the diagnosis of early gastric cancer: a review of the Japanese literature for the Western endoscopist. Gastrointest Endosc 2013; 78: 452–461. [Link]
19.
Hayashi N, et al. Endoscopic prediction of deep submucosal invasive carcinoma: validation of the narrow-band imaging international colorectal endoscopic (NICE) classification. Gastrointest Endosc 2013; 78: 625–632. [Link]
20.
Kudo S, et al. Diagnosis of colorectal tumorous lesions by magnifying endoscopy. Gastrointest Endosc 1996; 44: 8–14. [Link]
21.
Bouchard S and Devière J. endoscopic treatment for complex biliary and pancreatic duct injuries. Journal of Digestive Endoscopy 2014; 5: 2–12. [Link]
22.
Bouchard S, et al. Su1598 Endoscopic or combined endoscopic/percutaneous management of patients with complex bile duct injuries and biliary exclusion. Gastrointest Endosc 2015; 81 (Supplement): AB345–AB346. [Link]

Abstract

Liver cancer is the sixth most common cancer and the third leading cause of cancer-related death. Hepatocellular carcinoma (HCC) accounts for about 90% of cases and mostly arises in chronic liver disease, especially cirrhosis. Viral hepatitis remains a leading cause, but alcohol-related disease and MASLD are rising. With immune checkpoint inhibitors transforming HCC management, it is timely to highlight common mistakes across screening, staging, diagnosis and treatment.

Topics

Digestive Oncology Hepatobiliary

Published

2026

More Like This:

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Christos Triantos Christos Triantos, Ioannis Elefsiniotis, Spyridon Pantzios

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

Henit Yanai Henit Yanai

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

Sanjay Pandanaboyana Sanjay Pandanaboyana

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

Laura Leeuwenburgh Laura Leeuwenburgh

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Egle Dieninyte - Misiune Egle Dieninyte - Misiune, Giuseppe Vanella

Episode 9: Harmonising Gastroenterology Training Across Europe

Episode 9: Harmonising Gastroenterology Training Across Europe

Mohsan Subhani Mohsan Subhani, Sophie Schlosser-Hupf, Henriette Heinrich

UEG Standards and Guidelines
Clinical Practice Guideline
Share via Email Share on Facebook Share on X Share on LinkedIn Share on Bluesky

Log in to continue.

This content is part of Gutflix. Log in with your myUEG account, or create one free, to watch it.

Log In Create a free account

Not sure what you can access? Learn more about account types.

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

Henit Yanai

Summary

AI Generated

Summary is not available for this content yet.

Download PDF

Was this helpful?

Thanks for your feedback.

This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

Guideline

Introduction

The therapeutic landscape of inflammatory bowel disease [IBD] has undergone a profound transformation with the advent of novel immunosuppressive and biologic agents. These advancements have revolutionised the management of Crohn’s disease [CD] and ulcerative colitis [UC], enabling tighter control of inflammation and significantly improved patient outcomes. However, while older treatment strategies, including prolonged corticosteroids, purine analogues, and anti-tumour necrosis factor [TNF]/thiopurine combination therapy, carried a substantial immunosuppressive burden, the expanding therapeutic armamentarium introduces new agents with distinct infection risk profiles that require updated, evidence-based guidance. By definition, opportunistic infections are infections caused by organisms that infrequently induce disease in immunocompetent hosts but can result in significant morbidity or mortality in immunocompromised individuals. As treatment strategies increasingly rely on potent modulation of the immune system, ranging from traditional thiopurines to advanced small molecules, a structured, evidence-based approach to infection prevention, diagnosis, and management has become indispensable for the clinician. The European Crohn’s and Colitis Organisation [ECCO] has long recognised this clinical imperative, previously publishing consensus statements in 2009 and 2014, followed by a comprehensive guideline in 2021. This 2026 update is warranted by the rapid expansion of the therapeutic armamentarium, specifically the introduction of newer small molecules, advanced biologics, and evolving vaccination strategies. This update integrates the most recent data on risk stratification, viral, bacterial, mycobacterial, and vaccine-preventable infections, emphasising a preventative strategy tailored to the contemporary IBD treatment paradigm.

Publisher

European Crohn’s and Colitis Organisation logo
European Crohn’s and Colitis Organisation

Guideline

Clinical Practice Guideline

Topics

IBD

Citation

Journal of Crohn's and Colitis, Volume 20, Issue 7, July 2026

Published

2026

More Like This:

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Christos Triantos Christos Triantos, Ioannis Elefsiniotis, Spyridon Pantzios

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

Henit Yanai Henit Yanai

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

Sanjay Pandanaboyana Sanjay Pandanaboyana

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

Laura Leeuwenburgh Laura Leeuwenburgh

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Egle Dieninyte - Misiune Egle Dieninyte - Misiune, Giuseppe Vanella

Episode 9: Harmonising Gastroenterology Training Across Europe

Episode 9: Harmonising Gastroenterology Training Across Europe

Mohsan Subhani Mohsan Subhani, Sophie Schlosser-Hupf, Henriette Heinrich

UEG Standards and Guidelines
Clinical Practice Guideline
Share via Email Share on Facebook Share on X Share on LinkedIn Share on Bluesky

Log in to continue.

This content is part of Gutflix. Log in with your myUEG account, or create one free, to watch it.

Log In Create a free account

Not sure what you can access? Learn more about account types.

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

Sanjay Pandanaboyana

Summary

AI Generated

Summary is not available for this content yet.

Download PDF

Was this helpful?

Thanks for your feedback.

This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

Guideline

ABSTRACT

Pain is often the presenting symptom of acute pancreatitis (AP) and has a prognostic significance, with poorly treated pain affecting patient outcomes. Despite this, there are currently no international recommendations for pain management in patients admitted with AP. This current guideline was developed following the United European Gastroenterology framework for the development of high-quality clinical guidelines. Nine working groups were formed to develop statements on pain management in AP from admission to discharge. After systematic literature reviews, the evidence was evaluated according to the Grading of Recommendations Assessment, Development, and Evaluation methodology, as appropriate. Statements and comments were developed by the working groups and voted using three rounds of Delphi method. The guidelines concluded that acute postoperative pain management guidelines are applicable for treating acute pain due to AP. The numerical rating scale is preferred for pain assessment because of better compliance. Opioids currently form the cornerstone of severe pain management. Potent opioids such as buprenorphine and pentazocine provide superior pain relief over non-opioid medications and decrease the need for rescue analgesia. Current evidence does not consistently demonstrate harm from opioids in AP. In patients with severe pain, safety concerns should not delay the timely use of opioids to ensure adequate pain management. Specific recommendations concerning the use of epidural analgesia, acupuncture and management of pain in the paediatric population and during pregnancy are provided based on evidence and expert opinions. Finally, the unmet needs for future research were discussed and proposed.

Guideline

Clinical Practice Guideline

Topics

Pancreas

Citation

United European Gastroenterology Journal, 2026

Published

2026

More Like This:

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Christos Triantos Christos Triantos, Ioannis Elefsiniotis, Spyridon Pantzios

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

Henit Yanai Henit Yanai

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

Sanjay Pandanaboyana Sanjay Pandanaboyana

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

Laura Leeuwenburgh Laura Leeuwenburgh

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Egle Dieninyte - Misiune Egle Dieninyte - Misiune, Giuseppe Vanella

Episode 9: Harmonising Gastroenterology Training Across Europe

Episode 9: Harmonising Gastroenterology Training Across Europe

Mohsan Subhani Mohsan Subhani, Sophie Schlosser-Hupf, Henriette Heinrich

UEG Standards and Guidelines
Clinical Practice Guideline
Share via Email Share on Facebook Share on X Share on LinkedIn Share on Bluesky

Log in to continue.

This content is part of Gutflix. Log in with your myUEG account, or create one free, to watch it.

Log In Create a free account

Not sure what you can access? Learn more about account types.

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

Laura Leeuwenburgh

Summary

AI Generated

Summary is not available for this content yet.

Download PDF

Was this helpful?

Thanks for your feedback.

This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

Guideline

ABSTRACT

Background

Pancreatic cancer remains one of the most lethal cancers despite extensive efforts and research conducted over the past decades. To effectuate groundbreaking improvements in pancreatic cancer treatment, interdisciplinary and international collaboration is essential. Evidence-based guidelines, including state-of-the-art evidence and expert opinion, are crucial to guide medical specialists, researchers, and patients, especially on issues where consensus is still lacking. This article describes the methodological protocol for the development of the European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer. The guideline aims to identify current knowledge gaps on pancreatic cancer management, develop questions based on these knowledge gaps, and answer these questions with evidence-based recommendations supplemented, when evidence is lacking, with expert advice for treatment and future research.

Methods

This guideline development protocol is developed according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. The process is structured into six stages: First, 13 theme-based multidisciplinary working groups are established, comprising representatives from 30 European medical and patient societies. Second, these working groups identify the most relevant current knowledge gaps on pancreatic cancer within their theme and formulate key questions. Third, the available evidence to answer these key questions is obtained through systematic reviews and the certainty of evidence is assessed using the GRADE approach. Fourth, recommendations are developed based on the available evidence. Fifth, all participants reach consensus on the recommendations through a modified Delphi process. Sixth, the recommendations are discussed during an open conference, including an external validation committee.

Discussion

This methodological protocol of the European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer is designed to identify key knowledge gaps across 13 themes and formulate evidence-based recommendations. This guideline initiative unites 30 European medical and patient societies for pancreatic cancer.

Summary

  • Methodological protocol of an international multi-disciplinary guideline involving 30 European medical and patient societies.

  • This protocol highlights the six stages of the guideline development process, adhering to the key principles of the GRADE methodology, and thereby aims to maximise transparency and methodological quality.

  • With addressing knowledge gaps, this guideline will uncover areas with limited evidence. A priority rating for research needs, based on a survey, will be established, highlighting areas where future research is most warranted.

Guideline

Clinical Practice Guideline

Topics

Pancreas

Citation

Clinical and Public Health Guidelines 3 (2026)

Published

2026

More Like This:

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Christos Triantos Christos Triantos, Ioannis Elefsiniotis, Spyridon Pantzios

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

Henit Yanai Henit Yanai

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

Sanjay Pandanaboyana Sanjay Pandanaboyana

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

Laura Leeuwenburgh Laura Leeuwenburgh

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Egle Dieninyte - Misiune Egle Dieninyte - Misiune, Giuseppe Vanella

Episode 9: Harmonising Gastroenterology Training Across Europe

Episode 9: Harmonising Gastroenterology Training Across Europe

Mohsan Subhani Mohsan Subhani, Sophie Schlosser-Hupf, Henriette Heinrich

UEG Podcast Episode
New
UEG Podcast
Share via Email Share on Facebook Share on X Share on LinkedIn Share on Bluesky

Log in to continue.

This content is part of Gutflix. Log in with your myUEG account, or create one free, to watch it.

Log In Create a free account

Not sure what you can access? Learn more about account types.

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Giuseppe Vanella, Egle Dieninyte - Misiune

Summary

AI Generated

Summary is not available for this content yet.

Download PDF

Was this helpful?

Thanks for your feedback.

This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

Abstract

Topics

Endoscopy

Published

2026

More Like This:

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Christos Triantos Christos Triantos, Ioannis Elefsiniotis, Spyridon Pantzios

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

Henit Yanai Henit Yanai

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

Sanjay Pandanaboyana Sanjay Pandanaboyana

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

Laura Leeuwenburgh Laura Leeuwenburgh

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Egle Dieninyte - Misiune Egle Dieninyte - Misiune, Giuseppe Vanella

Episode 9: Harmonising Gastroenterology Training Across Europe

Episode 9: Harmonising Gastroenterology Training Across Europe

Mohsan Subhani Mohsan Subhani, Sophie Schlosser-Hupf, Henriette Heinrich

UEG Podcast Episode
Journal Podcast
Share via Email Share on Facebook Share on X Share on LinkedIn Share on Bluesky

Log in to continue.

This content is part of Gutflix. Log in with your myUEG account, or create one free, to watch it.

Log In Create a free account

Not sure what you can access? Learn more about account types.

Episode 9: Harmonising Gastroenterology Training Across Europe

Mohsan Subhani, Sophie Schlosser-Hupf, Henriette Heinrich

Summary

AI Generated

Summary is not available for this content yet.

Download PDF

Was this helpful?

Thanks for your feedback.

This summary was generated by an AI large language model based on the content transcript. It is for informational purposes only and should not be considered a substitute for clinical judgment. Always rely on your professional expertise and the full clinical context when making clinical decisions.

Abstract

Topics

Education & Training

Published

2026

More Like This:

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Mistakes in the management of hepatocellular carcinoma and how to avoid them

Christos Triantos Christos Triantos, Ioannis Elefsiniotis, Spyridon Pantzios

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

Henit Yanai Henit Yanai

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations

Sanjay Pandanaboyana Sanjay Pandanaboyana

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

The European Multidisciplinary Evidence-Based Guideline on Pancreatic Cancer: Methodological Protocol

Laura Leeuwenburgh Laura Leeuwenburgh

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Best of UEG Week 2026 - Endoscopy with Giuseppe Vanella

Egle Dieninyte - Misiune Egle Dieninyte - Misiune, Giuseppe Vanella

Episode 9: Harmonising Gastroenterology Training Across Europe

Episode 9: Harmonising Gastroenterology Training Across Europe

Mohsan Subhani Mohsan Subhani, Sophie Schlosser-Hupf, Henriette Heinrich

The global reference point for the digestive health community

Platform Publisher

United European Gastroenterology

Wickenburggasse 1 1080 Vienna, Austria

Contact us

support@ueg.eu

ueg.eu

T: +43 1 997 1639

Legal

Terms & Conditions

Imprint

Privacy Policy

Explore

My Bookmarks

My recommendations

My fields of interest

© 2026 United European Gastroenterology

Change fields of interest

These fields are selected based on the interests in your myUEG profile.
Click the item to unselect it. You can select multiple items.