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UEG Week Berlin 2025 Recordings Gut Guide online

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Free for all myUEG account holders. Your access level is set automatically based on your occupation. Medical professionals get full access to all content. If you are a non-medical user, you can only access UEG Week content from congresses you attended.

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Introduction

Complete excision of upper gastrointestinal sub-epithelial lesions (SELs) eliminates diagnostic uncertainty, obviates the need for surveillance and may be necessary for definitive diagnosis and management. Current guidelines lack precision and cohesion, and surgery is associated with significant morbidity. Herein, we describe and report on the outcomes of our SEL algorithm for endoscopic (SAFE) resection.

Aims & Methods

SELs were enrolled prospectively over 115 months until March 2023. All underwent axial (CT) imaging and endoscopic-ultrasonography (EUS) to exclude a large exophytic component or invasion into local structures, and assess for muscularis propria involvement.

Results

106 SELs were resected (mean age 60.6±13.4, 51.9% male; 41 oesophageal, 65 gastric). Oesophageal SELs underwent ESD (n=22) or STER if MP involvement was suspected (n=19). Gastric SELs underwent STER (n=6 at cardia), ESD (n=47) or exposing-EFTR (n=12). Technical success was 97.6% and 92.3% respectively. Five (7.7%) were completed laparoscopically due to deep and broad full-thickness involvement. Five (7.7%) required laparoscopic gastrotomy and surgical retrieval after successful resection and closure due to a large lesion size (mean 47 mm). There was no delayed bleeding, perforation or recurrence at a median of 13 months.

Conclusion

Upper GI SELs are effectively and safely treated by endoscopic resection. The SAFE approach provides a framework that facilitates structured decision-making. Oesophageal SELs suspected to involve the MP should undergo STER. Gastric SELs can be best managed by ESD with a view to proceed to exposing-EFTR. A laparoscopic UGI surgeon should be available in case surgical retrieval of the specimen or laparoscopic completion is required.

Disclosure

Michael J. Bourke: Research Support: Olympus, Cook Medical, Boston Scientific.

A SUB-EPITHELIAL LESION ALGORITHM FOR ENDOSCOPIC (SAFE) RESECTION IN THE UPPER GASTROINTESTINAL TRACT

Sunil Gupta 1, Julia Gauci 2, Timothy O'Sullivan 1, Oliver Cronin 3, Anthony Whitfield 1, Ana Craciun 2, Halim Awadie 2, Jing Yang 2, Francesco Vito Mandarino 2, Vu Kwan 2, Eric Lee 2, Nicholas G Burgess 1, Michael John Bourke 1

1 Westmead Hospital, Sydney, Australia|||University of Sydney, Sydney, Australia

2 Westmead Hospital, Sydney, Australia

3 University of Sydney, Sydney, Australia|||Westmead Hospital, Sydney, Australia

Conference

UEG Week Vienna 2024

Topics

Oesophagus

Submission format

Abstract

Session

OESOPHAGEAL, GASTRIC AND DUODENAL (Posters)

Citation

United European Gastroenterology Journal 2024; 12 (Supplement 8)

Published

2024

UEG Online Course

accredited

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This interactive course explores why optimising polyp detection is central to high-quality colonoscopy and its direct impact on morbidity and mortality. Designed for general gastroenterologists and young endoscopists, the course addresses key quality indicators, bowel preparation, scoping techniques, and the integration of AI for improved detection. Participants will learn to interpret and apply optical diagnosis systems (NICE, WASP, LST-classification, BLINC) and to choose appropriate therapeutic strategies tailored to polyp type and patient context. Surveillance intervals and outcome factors, including family history and syndromes, will be discussed in line with ESGE guidelines. Case-based discussions will focus on communication with patients regarding diagnosis and management. By combining expert testimony, videos, and practical strategies, the course aims to improve participants’ endoscopic practice, ensuring earlier detection, appropriate treatment, and better long-term outcomes.

Target Audience:

Gastroenterologists (in training)
Other physicians and surgeons
Nurses
Medical students

Impact of Polyp Detection in Colonoscopy

Raf Bisschops, Manuele Furnari, Veronique Van der Voort, Pieter Sinonquel

Event

Impact of Polyp Detection in Colonoscopy

Topics

Endoscopy Colorectal

Accreditation status

accredited

Duration

1 hour

Published

2025

UEG Podcast Episode

Journal Podcast

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Episode 9: Harmonising Gastroenterology Training Across Europe

Mohsan Subhani, Sophie Schlosser-Hupf, Henriette Heinrich

Topics

Education & Training

Published

2026

UEG Online Course

accredited

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Building on the foundations covered in Part 1, this second course provides a deeper dive into the essential steps of guideline development. Participants will learn how to identify when a new guideline or statement is warranted, formulate focused clinical questions using PICO, and translate these into comprehensive search strategies. The course also covers the application of GRADE domains to assess evidence certainty, and guides learners through the Evidence-to-Decision framework. Finally, it clarifies the difference between good practice statements and formal guideline recommendations, ensuring participants gain the practical skills needed to contribute effectively to high-quality guideline development.

Target Audience:

Healthcare professionals interested in developing guidelines
Patients and stakeholders interested in understanding the process of guideline development

How to develop guidelines - Part 2

Yasuko Maeda, Adele Sayers

Event

How to develop guidelines - Part 2

Topics

Primary Care Education & Training

Accreditation status

accredited

Duration

1 hour

Published

2025

UEG Podcast Episode

UEG Podcast

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AI Essentials: Basics and upper GI (UEG Talks rewind)

Louis Liu, Alanna Ebigbo, Pradeep Mundre

Topics

Endoscopy

Published

2025

UEG Mistakes In Articles

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Pancreatic exocrine insufficiency (PEI) is a common yet frequently under-recognised cause of maldigestion, malabsorption, and malnutrition. Although traditionally associated with primary pancreatic disorders such as chronic pancreatitis, cystic fibrosis, pancreatic cancer, or pancreatic surgery, it is now evident that PEI also occurs in a wide range of extra-pancreatic conditions and clinical settings. Advances in diagnostic testing and expanding clinical awareness have improved detection; however, significant misconceptions persist regarding when to suspect PEI; how to interpret diagnostic tests; and how to initiate, optimise, and monitor pancreatic enzyme replacement therapy (PERT). In everyday practice, these errors may lead to delayed diagnosis, inappropriate treatment, persistent symptoms, and preventable nutritional deficiencies. This “Mistakes in…” article highlights common pitfalls in the diagnosis and management of PEI, focusing on inappropriate reliance on faecal elastase testing, failure to recognise secondary causes, undertreatment with PERT, and inadequate nutritional assessment. By addressing these frequent mistakes, we aim to promote a more structured, patient-centred, and evidence-informed approach to PEI that improves clinical outcomes and quality of life.